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Hemolysis or haemolysis (), also known by several other names, is the rupturing (lysis) of red blood cells (erythrocytes) and the release of their contents (cytoplasm) into surrounding fluid (e.g. blood plasma). Hemolysis may occur in vivo or in vitro (inside or outside the body).
Hemolysins damage the host cytoplasmic membrane, causing cell lysis and death. The activity of these toxins is most easily observed with assays involving the lysis of red blood cells (erythrocytes). Some hemolysins attack the phospholipid of the host cytoplasmic membrane. Because the phospholipid lecithin (phosphatidylcholine) is often used as a substrate, these enzymes are called lecithinases or phospholipases. Some hemolysins affects the sterols of the host cytoplasmic membrane.
Others suffer acute anemic reactions known as hemolysis when they come into contact with triggering substances often found in foods, medicines, and hygiene products.
Others suffer acute anemic reactions (known as hemolysis) when they come into contact with triggering substances often found in foods, medicines, and hygiene products.
Other symptoms are severe anemia due to hemolysis, which is destruction of the red blood cells, hemoglobinuria, which is hemoglobin in the urine, due to hemolysis, and pulmonary edema, or fluid buildup in the lungs.
Essentially, when triggering substances are eliminated, hemolysis ceases and both acute and long-range implications are abated.
Items such as soy -- an immensely widespread additive that often triggers hemolysis in G6PD sufferers -- are hidden in many products and are thus ingested by people despite their best attempts to avoid it, since even when it isn't expressly mentioned on a label it can be part of any of the additives, binders, and preservatives (the same is true for sulfites and other oxidants).
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