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Vaprisol is approved by the FDA for treatment of euvolemic and more recently hypervolemic hyponatremia and is given IV.
People at highest risk of acute phosphate nephropathy are those over the age of 55, those who are hypervolemic or suffer from decreased intravascular volume, those who have baseline kidney disease, bowel obstruction or active colitis, and those who are taking medications that affect renal function.
Vaprisol is indicated for the treatment of euvolemic and hypervolemic hyponatremia in hospitalized patients.
Furthermore, in contrast to patients with a low ejection fraction, patients with a normal ejection fraction could be hypovolemic (low blood volume), normovolemic (normal blood volume), or hypervolemic (high blood volume).
(low blood volume), normovolemic (normal blood volume), or hypervolemic (high blood volume).
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